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Funktionen des endokrinen Systems

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Author(s): K. Brück

Publication date (Print): 1977

Publisher: Springer Berlin Heidelberg

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Hypothalamic polypeptide that inhibits the secretion of immunoreactive pituitary growth hormone.

P Brazeau, W. Vale, R Burgus … (1973)

A peptide has been isolated from ovine hypothalamus which, at 1 x 10(-9)M, inhibits secretion in vitro of immunoreactive rat or human growth hormones and is similarly active in vivo in rats. Its structure is H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH The synthetic replicate is biologically active.