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Prodrugs and Targeted Delivery
edited_book
Editor(s):
Jarkko Rautio
Publication date
(Print):
December 15 2010
Publisher:
Wiley-VCH Verlag GmbH & Co. KGaA
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RNA drug delivery
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Book
ISBN (Electronic):
9783527633166
ISBN (Print):
9783527326037
Publication date (Print):
December 15 2010
DOI:
10.1002/9783527633166
SO-VID:
9aee75c7-8cb1-4aa9-acae-26788a363a65
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Book chapters
pp. I
Front Matter
pp. 1
Prodrug Strategies in Drug Design
pp. 31
The Molecular Design of Prodrugs by Functional Group
pp. 61
Intellectual Property Primer on Pharmaceutical Patents with a Special Emphasis on Prodrugs and Metabolites
pp. 79
Increasing Lipophilicity for Oral Drug Delivery
pp. 111
Modulating Solubility Through Prodrugs for Oral and IV Drug Delivery
pp. 133
Prodrugs Designed to Target Transporters for Oral Drug Delivery
pp. 153
Topical and Transdermal Delivery Using Prodrugs: Mechanism of Enhancement
pp. 181
Ocular Delivery Using Prodrugs
pp. 207
Reducing Presystemic Drug Metabolism
pp. 231
Enzyme-Activated Prodrug Strategies for Site-Selective Drug Delivery
pp. 253
Prodrug Approaches for Central Nervous System Delivery
pp. 271
Directed Enzyme Prodrug Therapies
pp. 345
Improving the Use of Drug Combinations Through the Codrug Approach
pp. 385
Soft Drugs
pp. 415
Pharmacokinetic and Biopharmaceutical Considerations in Prodrug Discovery and Development
pp. 453
The Impact of Pharmacogenetics on the Clinical Outcomes of Prodrugs
pp. 483
Index
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