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Industrial Perspectives

edited_book

Author(s): Andreas Kandelbauer , Manfred Rahe , Rudolf W. Kessler

Publication date (Online): January 01 2013

Publisher: Wiley-VCH Verlag GmbH & Co. KGaA

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A review of near infrared spectroscopy and chemometrics in pharmaceutical technologies.

Sean Lema, Yves Roggo, P Chalus … (2007)

Near-infrared spectroscopy (NIRS) is a fast and non-destructive analytical method. Associated with chemometrics, it becomes a powerful tool for the pharmaceutical industry. Indeed, NIRS is suitable for analysis of solid, liquid and biotechnological pharmaceutical forms. Moreover, NIRS can be implemented during pharmaceutical development, in production for process monitoring or in quality control laboratories. This review focuses on chemometric techniques and pharmaceutical NIRS applications. The following topics are covered: qualitative analyses, quantitative methods and on-line applications. Theoretical and practical aspects are described with pharmaceutical examples of NIRS applications.