Lithium-ion batteries are a key technology for energy storage not only in consumer electronics but also in e-mobility and stationary applications. However, in order to guarantee the success of lithium-ion batteries in the long term, improvements related to performance, lifetime and production costs need to be made. Mastery of the highly interlinked process chain in lithium-ion battery manufacturing is a challenge and often acquired on the basis of experience. This paper illustrates the complexity of this process chain with a special focus on the roll-to-roll manufacturing of electrodes and discusses the application of a quality management system in lithium-ion battery production.