Uncovering the Serine Hydrolytic Landscape of Mycobacterium tuberculosis

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Abstract

<p class="first" id="P1">A new study utilizing a click-chemistry-enabled fluorophosphonate for activity-based identification of serine hydrolases, labeled a range of proteins including previously annotated hypotheticals. The application of this technology on actively replicating and non-replicating <i>Mycobacterium tuberculosis</i> gives us a glimpse of its serine hydrolytic landscape during different stages of metabolic activity. </p>

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Journal

Title: Cell Chemical Biology

Abbreviated Title: Cell Chemical Biology

Publisher: Elsevier BV

ISSN (Print): 24519456

Publication date Created: February 2016

Publication date (Print): February 2016

Volume: 23

Issue: 2

Pages: 209-211

Article

DOI: 10.1016/j.chembiol.2016.02.002

PMC ID: 6350241

PubMed ID: 26971871

SO-VID: 166d3125-0059-4dcd-b0ac-48e1e92fad57

License:

https://www.elsevier.com/tdm/userlicense/1.0/

https://www.elsevier.com/open-access/userlicense/1.0/

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