Effect of pronounced weight loss on the nontraditional cardiovascular risk marker matrix metalloproteinase-9 in middle-aged morbidly obese women. – ScienceOpen
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      Effect of pronounced weight loss on the nontraditional cardiovascular risk marker matrix metalloproteinase-9 in middle-aged morbidly obese women.

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          Abstract

          Obesity is associated with increased morbidity and mortality from atherosclerotic disease. Nontraditional cardiovascular risk factors such as C-reactive protein (CRP) and interleukin-6 (IL-6) are elevated in obese subjects and weight loss is associated with an attenuation of these risk factors. Matrix metalloproteinase-9 (MMP-9) has been linked to plaque rupture, and is, thus, a candidate marker of future myocardial events. The aim of this study was to determine the influence of weight loss on MMP-9 plasma concentrations.

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          Author and article information

          Journal
          Int J Obes (Lond)
          International journal of obesity (2005)
          Springer Science and Business Media LLC
          0307-0565
          0307-0565
          May 2005
          : 29
          : 5
          Affiliations
          [1 ] Clinical Department of Internal Medicine, Clinical Division of General Internal Medicine, Medical University Innsbruck, Austria.
          Article
          0802897
          10.1038/sj.ijo.0802897
          15685246
          418004aa-74a8-46f5-aac6-db8f7d705d1c
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