Recurrent primary intracranial synovial sarcoma, a case report and review of the literature

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Synovial sarcoma (SS) occurs in various parts of the body, predominantly in the extremities. It also occurs in organs without synovial structures. The intracranial disease has been reported as metastasis, but primary intracranial SS has been reported rarely. We report a patient with hemiplegia and a mass on the brain CT. Pathology showed SS with no extracranial pathology.

Abstract

Synovial sarcoma (SS) is one of the most common sarcomas of soft tissue, and it mostly occurs in the lower extremities. It can cause metastasic disease, especially in the lungs, bones, and lymph nodes. Metastasis in the brain is very rare. Primary intracranial SS has also been reported in extremely rare cases. In this article, we study the case of a 28‐year‐old man with primary intracranial SS.

Related collections

Most cited references 29

Record: found
Abstract: found
Article: not found

The 2020 WHO Classification :
What’s New in Soft Tissue Tumor Pathology?

Michael Kallen, Jason Hornick (2021)

The fifth edition of the World Health Organization Classification of Tumors of Soft Tissue and Bone was published in early 2020. The revisions reflect a consensus among an international expert editorial board composed of soft tissue and bone pathologists, geneticists, a medical oncologist, surgeon, and radiologist. The changes in the soft tissue tumor chapter notably include diverse, recently described tumor types (eg, atypical spindle cell/pleomorphic lipomatous tumor, angiofibroma of soft tissue, and CIC-rearranged sarcoma), new clinically significant prognostic information for a variety of existing entities (eg, dedifferentiated liposarcoma and solitary fibrous tumor), and a plethora of novel genetic alterations, some of practical diagnostic relevance (eg, NAB2-STAT6 in solitary fibrous tumor, FOSB rearrangements in epithelioid hemangioma and pseudomyogenic hemangioendothelioma, and SUZ12 or EED mutations in malignant peripheral nerve sheath tumor, leading to loss of H3K27 trimethylation). In this review, we highlight the major changes to the soft tissue chapter in the 2020 World Health Organization Classification, as well as the new chapter on undifferentiated small round cell sarcomas, with a focus on updates in diagnostic categories, prognostication, and novel markers. Recent discoveries in molecular genetics are also discussed, particularly those of immediate utility in differential diagnosis, including protein correlates detectable using immunohistochemistry.

0 comments Cited 103 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: found
Article: found

Is Open Access

Malignant small round cell tumors

Arvind Rajwanshi, Radhika Srinivas, Gautam Upasana (2009)

Malignant small round cell tumors are characterised by small, round, relatively undifferentiated cells. They generally include Ewing's sarcoma, peripheral neuroectodermal tumor, rhabdomyosarcoma, synovial sarcoma, non-Hodgkin's lymphoma, retinoblastoma, neuroblastoma, hepatoblastoma, and nephroblastoma or Wilms’ tumor. Other differential diagnoses of small round cell tumors include small cell osteogenic sarcoma, undifferentiated hepatoblastoma, granulocytic sarcoma, and intraabdominal desmoplastic small round cell tumor. Differential diagnosis of small round cell tumors is particularly difficult due to their undifferentiated or primitive character. Tumors that show good differentiation are generally easy to diagnose, but when a tumor is poorly differentiated, identification of the diagnostic, morphological features is difficult and therefore, no definitive diagnosis may be possible. As seen in several study reports, fine needle aspiration cytology (FNAC) has become an important modality of diagnosis for these tumors. The technique yields adequate numbers of dissociated, viable cells, making it ideally suitable for ancillary techniques. Typically, a multimodal approach is employed and the principal ancillary techniques that have been found to be useful in classification are immunohistochemistry and immunophenotyping by flow cytometry, reverse transcriptase polymerase chain reaction (RT-PCR), fluorescence in situ hybridization (FISH), and electron microscopy. However, the recent characterization of chromosomal breakpoints and the corresponding genes involved in malignant small round cell tumors means that it is possible to use molecular genetic approaches for detection.

0 comments Cited 57 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: found
Article: found

Is Open Access

The evidence base for physiotherapy in myalgic encephalomyelitis/chronic fatigue syndrome when considering post-exertional malaise: a systematic review and narrative synthesis

Marjon E. A. Wormgoor, Sanne Rodenburg (2021)

Background Due to the inconsistent use of diagnostic criteria in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), it is unsure whether physiotherapeutic management regarded effective in ME/CFS is appropriate for patients diagnosed with criteria that consider post-exertional malaise (PEM) as a hallmark feature. Purpose To appraise current evidence of the effects of physiotherapy on symptoms and functioning in ME/CFS patients in view of the significance of PEM in the applied diagnostic criteria for inclusion. Methods A systematic review of randomized controlled trials published over the last two decades was conducted. Studies evaluating physiotherapeutic interventions for adult ME/CFS patients were included. The diagnostic criteria sets were classified into three groups according to the extent to which the importance of PEM was emphasized: chronic fatigue (CF; PEM not mentioned as a criterion), CFS (PEM included as an optional or minor criterion) or ME (PEM is a required symptom). The main results of included studies were synthesized in relation to the classification of the applied diagnostic criteria. In addition, special attention was given to the tolerability of the interventions. Results Eighteen RCTs were included in the systematic review: three RCTs with CF patients, 14 RCTs with CFS patients and one RCT covering ME patients with PEM. Intervention effects, if any, seemed to disappear with more narrow case definitions, increasing objectivity of the outcome measures and longer follow-up. Conclusion Currently, there is no scientific evidence when it comes to effective physiotherapy for ME patients. Applying treatment that seems effective for CF or CFS patients may have adverse consequences for ME patients and should be avoided.

0 comments Cited 48 times – based on 0 reviews      Review now

Bookmark

All references

Author and article information

Contributors

Zhale Tabrizi:

ORCID: https://orcid.org/0000-0002-4961-1713

zh.tb_1991@yahoo.com

Journal

Journal ID (nlm-ta): Clin Case Rep

Journal ID (iso-abbrev): Clin Case Rep

Journal ID (doi): 10.1002/(ISSN)2050-0904

Journal ID (publisher-id): CCR3

Title: Clinical Case Reports

Publisher: John Wiley and Sons Inc. (Hoboken )

ISSN (Electronic): 2050-0904

Publication date (Electronic): 05 September 2022

Publication date Collection: September 2022

Volume: 10

Issue: 9 ( doiID: 10.1002/ccr3.v10.9 )

Electronic Location Identifier: e6273

Affiliations

[ ¹ ] Department of Radiology, Firouzgar Hospital Iran university of medical science Tehran Iran

[ ² ] Department of orthopaedics surgery, Alzahra hospital Isfahan university of medical science Isfahan Iran

[ ³ ] Department of Radiology Iran university of medical science Tehran Iran

Author notes

[*] [* ] Correspondence

Zhale Tabrizi, Department of Radiology, Iran university of medical science, Tehran, Iran.

Email: zh.tb_1991@ 123456yahoo.com

Author information

Zhale Tabrizi https://orcid.org/0000-0002-4961-1713

Article

Publisher ID: CCR36273 Other ID: CCR3-2022-05-1092.R2

DOI: 10.1002/ccr3.6273

PMC ID: 9445261

PubMed ID: 36093454

SO-VID: 568b81ab-007d-41b6-9789-143a75b02ddb

License:

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

History

Date revision received : 19 July 2022

Date received : 16 May 2022

Date accepted : 07 August 2022

Page count

Figures: 5, Tables: 0, Pages: 6, Words: 2653

Custom metadata

source-schema-version-number 2.0

cover-date September 2022

details-of-publishers-convertor Converter:WILEY_ML3GV2_TO_JATSPMC version:6.1.8 mode:remove_FC converted:06.09.2022

Keywords: metastatic intracranial synovial sarcoma,primary intracranial synovial sarcoma,synovial sarcoma

Data availability:

Keywords: metastatic intracranial synovial sarcoma, primary intracranial synovial sarcoma, synovial sarcoma

Comments

Comment on this article

scite_

Smart Citations

Citing PublicationsSupportingMentioningContrasting

View Citations

See how this article has been cited at scite.ai

scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.

Cited by 1

Olfactory groove monophasic sinovial sarcoma and von Recklinghausen’s disease: A case report and literature review
Authors: Breno Nery, Joaquim Fechine de Alencar Neto, Layssa Rhossana dos Santos Melo …

See all cited by

Most referenced authors 649

See all reference authors