The digital supply chain has become an integral part of modern business operations, enabling efficient and streamlined processes. However, with the rapid advancement of technology, the supply chain landscape has become increasingly vulnerable to cyber threats and attacks. This chapter explores the critical issue of cybersecurity within the context of the digital supply chain, aiming to equip professionals and practitioners with the knowledge and strategies to safeguard their operations. Lastly, the chapter sheds light on emerging technologies and future trends and concludes with a call to action for securing the digital supply chain. It also highlights the future challenges and directions in cybersecurity for the supply chain, urging professionals to stay vigilant and adapt to evolving strategies and technologies. Overall, this chapter serves as a comprehensive guide for securing the digital supply chain, empowering readers to fortify their operations against cyber threats and ensure the resilience of their supply chain networks.