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      Carcinoma de glándulas sebáceas limitado a conjuntiva bulbar Translated title: Sebaceous gland carcinoma restricted to bulb conjunctiva

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          Abstract

          El carcinoma de glándulas sebáceas es un tumor infrecuente que puede desarrollarse a partir de cualquier glándula sebácea en la piel. El 75 % de las veces es de origen ocular y afecta principalmente las glándulas de Zeiss, Meibomio y de la carúncula. Se caracteriza por un comportamiento agresivo, con alta probabilidad de invasión a piel, conjuntiva y córnea. Sin embargo, el compromiso de la conjuntiva como localización primaria es raro. Se presenta un caso con diagnóstico de carcinoma sebáceo de patrón nodular primario de la conjuntiva bulbar, atendido en el Hospital Universitario de Santander durante los años 2014-2016. El propósito del presente estudio es dar a conocer el caso de una patología infrecuente con pocos casos reportados en la literatura, enfatizar su importancia dentro de los diagnósticos diferenciales de masas en la conjuntiva y del estudio histopatológico como método para obtener un diagnóstico definitivo y realizar un abordaje temprano.

          Translated abstract

          Sebaceous gland carcinoma is an uncommon tumor that may derive from any sebaceous gland of the skin. In 75% of cases is ocular and mainly affects the Zeiss, Melbonium and caruncle glands. It is characterized for its aggressiveness, high probability of passing into the skin, the conjunctiva and the cornea. However, the involvement of the conjunctiva as a primary location is rare. This is a case diagnosed with sebaceous carcinoma of primary nodullary pattern of the bulb conjunctiva, which was seen at the university hospital of Santander from 2014 to 2016. The objective of the study was to show the case of an infrequent pathology with very few cases reported up to now in literature, to make emphasis on its importance within the differential diagnoses of masses present in the conjunctiva and of the histopathological study as a method to obtain a final diagnosis and to make an early intervention.

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          Primary sebaceous gland carcinoma of the bulbar conjunctiva without involvement of eyelid: A clinical dilemma

          Sebaceous gland carcinoma usually arises from the meibomian or Zeis glands within the eyelid, but tumor arising primarily from the conjunctiva, especially bulbar conjunctiva, is a rarity. We hereby report a case of a 50-year-old female who presented with a painless mass in the inferior limbus, encroaching the cornea and hanging over the lower eyelid without involving it. Imprint cytology was suggestive of adenosquamous carcinoma. Management consisted of wide local excision, cryotherapy to tumor bed, and topical 5-fluorouracil (5-FU) 1% preoperatively and postoperatively. Histopathologic analysis was in favor of sebaceous gland carcinoma. This case suggests that although sebaceous gland carcinoma commonly originates as a lid tumor, it can present as a bulbar conjunctival mass. Topical 5-FU is a viable and efficient cost-effective alternative for neo-adjuvant and adjuvant treatment of sebaceous gland carcinoma.
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            Nonmelanocytic tumors of the skin

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              Carcinoma sebáceo

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                Author and article information

                Journal
                oft
                Revista Cubana de Oftalmología
                Rev Cubana Oftalmol
                Editorial Ciencias Médicas (Ciudad de la Habana, , Cuba )
                0864-2176
                1561-3070
                March 2017
                : 30
                : 1
                Affiliations
                [01] Bucaramanga orgnameUniversidad Industrial de Santander orgdiv1Hospital Universitario de Santander Colombia
                Article
                S0864-21762017000100014 S0864-2176(17)03000100014
                9f51776c-e860-4d28-a2fd-cbbca288301c

                This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

                History
                : 18 August 2016
                : 21 November 2016
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 7, Pages: 0
                Product

                SciELO Cuba

                Categories
                PRESENTACIONES DE CASOS

                conjunctival neoplasias,sebaceous glands,carcinoma sebáceo,neoplasias de la conjuntiva,glándulas sebáceas,sebaceous carcinoma

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