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      Development and validation of a new knowledge, attitude, belief and practice questionnaire on leptospirosis in Malaysia

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          Abstract

          Background

          In Malaysia, leptospirosis is considered an endemic disease, with sporadic outbreaks following rainy or flood seasons. The objective of this study was to develop and validate a new knowledge, attitude, belief and practice (KABP) questionnaire on leptospirosis for use in urban and rural populations in Malaysia.

          Methods

          The questionnaire comprised development and validation stages. The development phase encompassed a literature review, expert panel review, focus-group testing, and evaluation. The validation phase consisted of exploratory and confirmatory parts to verify the psychometric properties of the questionnaire. A total of 214 and 759 participants were recruited from two Malaysian states, Kelantan and Selangor respectively, for the validation phase. The participants comprised urban and rural communities with a high reported incidence of leptospirosis. The knowledge section of the validation phase utilized item response theory (IRT) analysis. The attitude and belief sections utilized exploratory factor analysis (EFA) and confirmatory factor analysis (CFA).

          Results

          The development phase resulted in a questionnaire that included four main sections: knowledge, attitude, belief, and practice. In the exploratory phase, as shown by the IRT analysis of knowledge about leptospirosis , the difficulty and discrimination values of the items were acceptable, with the exception of two items. Based on the EFA, the psychometric properties of the attitude, belief, and practice sections were poor. Thus, these sections were revised, and no further factor analysis of the practice section was conducted. In the confirmatory stage, the difficulty and discrimination values of the items in the knowledge section remained within the acceptable range. The CFA of the attitude section resulted in a good-fitting two-factor model. The CFA of the belief section retained low number of items, although the analysis resulted in a good fit in the final three-factor model.

          Conclusions

          Based on the IRT analysis and factor analytic evidence, the knowledge and attitude sections of the KABP questionnaire on leptospirosis were psychometrically valid. However, the psychometric properties of the belief section were unsatisfactory, despite being revised after the initial validation study. Further development of this section is warranted in future studies.

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          Most cited references19

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          Applying item response theory (IRT) modeling to questionnaire development, evaluation, and refinement.

          Health outcomes researchers are increasingly applying Item Response Theory (IRT) methods to questionnaire development, evaluation, and refinement efforts. To provide a brief overview of IRT, to review some of the critical issues associated with IRT applications, and to demonstrate the basic features of IRT with an example. Example data come from 6,504 adolescent respondents in the National Longitudinal Study of Adolescent Health public use data set who completed to the 19-item Feelings Scale for depression. The sample was split into a development and validation sample. Scale items were calibrated in the development sample with the Graded Response Model and the results were used to construct a 10-item short form. The short form was evaluated in the validation sample by examining the correspondence between IRT scores from the short form and the original, and by comparing the proportion of respondents identified as depressed according to the original and short form observed cut scores. The 19 items varied in their discrimination (slope parameter range: .86-2.66), and item location parameters reflected a considerable range of depression (-.72-3.39). However, the item set is most discriminating at higher levels of depression. In the validation sample IRT scores generated from the short and long forms were correlated at .96 and the average difference in these scores was -.01. In addition, nearly 90% of the sample was classified identically as at risk or not at risk for depression using observed score cut points from the short and long forms. When used appropriately, IRT can be a powerful tool for questionnaire development, evaluation, and refinement, resulting in precise, valid, and relatively brief instruments that minimize response burden.
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            The globalization of leptospirosis: worldwide incidence trends.

            Leptospirosis continues to be a significant zoonosis of the developing world. Globalization, in the context of international travel, particularly for recreational activities and military expeditions, has led to increased exposure of individuals from the developed world to the disease, as recent outbreaks show. We evaluated the trends in annual leptospirosis incidence for individual countries worldwide through reports from national and international organizations, the published medical literature on the subject, and web searches with the terms 'leptospirosis' and the individual country names. Inter-country variations in leptospirosis incidence, when relevant official data were available, were also analyzed. The Caribbean and Latin America, the Indian subcontinent, Southeast Asia, Oceania, and to a lesser extent Eastern Europe, are the most significant foci of the disease, including areas that are popular travel destinations. Leptospirosis is a re-emerging zoonosis of global importance and unique environmental and social correlations. Attempts at global co-ordination and recognition of the true burden of an infectious disease with significant mortality should be encouraged.
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              Global Burden of Leptospirosis: Estimated in Terms of Disability Adjusted Life Years

              Background Leptospirosis, a spirochaetal zoonosis, occurs in diverse epidemiological settings and affects vulnerable populations, such as rural subsistence farmers and urban slum dwellers. Although leptospirosis can cause life-threatening disease, there is no global burden of disease estimate in terms of Disability Adjusted Life Years (DALYs) available. Methodology/Principal Findings We utilised the results of a parallel publication that reported global estimates of morbidity and mortality due to leptospirosis. We estimated Years of Life Lost (YLLs) from age and gender stratified mortality rates. Years of Life with Disability (YLDs) were developed from a simple disease model indicating likely sequelae. DALYs were estimated from the sum of YLLs and YLDs. The study suggested that globally approximately 2·90 million DALYs are lost per annum (UIs 1·25–4·54 million) from the approximately annual 1·03 million cases reported previously. Males are predominantly affected with an estimated 2·33 million DALYs (UIs 0·98–3·69) or approximately 80% of the total burden. For comparison, this is over 70% of the global burden of cholera estimated by GBD 2010. Tropical regions of South and South-east Asia, Western Pacific, Central and South America, and Africa had the highest estimated leptospirosis disease burden. Conclusions/Significance Leptospirosis imparts a significant health burden worldwide, which approach or exceed those encountered for a number of other zoonotic and neglected tropical diseases. The study findings indicate that highest burden estimates occur in resource-poor tropical countries, which include regions of Africa where the burden of leptospirosis has been under-appreciated and possibly misallocated to other febrile illnesses such as malaria.
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                Author and article information

                Contributors
                drzahir@usm.my
                wnarifin@usm.my
                drnazri@usm.my
                surianti@usm.my
                hjhzawaha@yahoo.com
                abubakar.rahman@moh.gov.my
                rukman@upm.edu.my
                malinaosman@upm.edu.my
                tengkuzetty@upm.edu.my
                pathman_19@hotmail.com
                masharithul@outlook.com
                norazlin@usm.my
                suhailah.sam@gmail.com
                sakinahsaudi@gmail.com
                nurulmunirahabdullah@gmail.com
                miranozmi@live.com
                zwah58@gmail.com
                aziahkb@usm.my
                Journal
                BMC Public Health
                BMC Public Health
                BMC Public Health
                BioMed Central (London )
                1471-2458
                7 March 2018
                7 March 2018
                2018
                : 18
                : 331
                Affiliations
                [1 ]ISNI 0000 0001 2294 3534, GRID grid.11875.3a, Department of Community Medicine, School of Medical Sciences, , Universiti Sains Malaysia, ; 16150 Kubang Kerian, Kelantan Malaysia
                [2 ]ISNI 0000 0001 2294 3534, GRID grid.11875.3a, Unit of Biostatistics and Research Methodology, School of Medical Sciences, , Universiti Sains Malaysia, ; Kubang Kerian, Kelantan Malaysia
                [3 ]Ministry of Health Malaysia, Institute of Behavioural Health Research, Jalan Rumah Sakit Bangsar, Kuala Lumpur, Malaysia
                [4 ]ISNI 0000 0001 2231 800X, GRID grid.11142.37, Department of Medical Microbiology and Parasitology, Faculty of Medicine and Health Sciences, , Universiti Putra Malaysia, ; Serdang, Selangor Malaysia
                [5 ]ISNI 0000 0001 0690 5255, GRID grid.415759.b, Disease Control Division, Complex E, Ministry of Health Malaysia, ; Putrajaya, Malaysia
                Author information
                http://orcid.org/0000-0002-5564-6111
                Article
                5234
                10.1186/s12889-018-5234-y
                5842588
                29514645
                a6a01dba-11dd-4267-8e98-62c394d632ac
                © The Author(s). 2018

                Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

                History
                : 13 May 2017
                : 28 February 2018
                Funding
                Funded by: FundRef http://dx.doi.org/10.13039/501100003093, Ministry of Higher Education, Malaysia;
                Award ID: UPM/700-2/1/LRGS/5526400
                Categories
                Research Article
                Custom metadata
                © The Author(s) 2018

                Public health
                leptospirosis,knowledge,attitude,belief,practice,questionnaires,development,validation
                Public health
                leptospirosis, knowledge, attitude, belief, practice, questionnaires, development, validation

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