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      The impact of health literacy interventions on glycemic control and self‐management outcomes among type 2 diabetes mellitus: A systematic review Translated title: 健康素养干预对2型糖尿病患者血糖控制和自我管理结果的影响:一项系统综述

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          Abstract

          Diabetes imposes an increasing health and economic burden on individuals living with it and their societies worldwide. Glycemic control is necessary to reduce morbidity and mortality of type 2 diabetes mellitus (T2DM). Self‐management is the primary tool for managing diabetes. Health literacy (HL) is the primary driver of self‐management activities. The aim of this review is to evaluate the impact of HL interventions on glycemic control and self‐management outcomes among T2DM. MEDLINE, CINAHL, PubMed, Cochrane, Scopus, and Web of Science were searched for eligible papers. Fifteen randomized controlled trials published in English between 1997 and 2021, used HL‐driven intervention, and measured the level of glycohemoglobin A1c (HbA1c) and self‐management of T2DM patients were included in this review. The findings showed that HL‐driven intervention had a positive impact on glycemic control and improved self‐management behaviors. The level of glycemic control and self‐management skills were improved through individual and telephone‐based intervention respectively. Community worker‐led interventions were effective in improvements in diabetes knowledge and self‐care behaviors; however, nurse‐led interventions were effective in glycemic control. Better glycemic control is achieved in hospital settings compared to outpatient settings. HL interventions yielded better improvement in self‐management among people with longer diabetes duration (more than 7 years). It was possible to achieve a large reduction in HbA1c level after a 3‐month intervention in hospital settings. HL‐driven interventions are effective in glycemic and diabetes self‐management outcomes.

          Abstract

          Highlights

          • Health literacy (H)L‐driven interventions were effective in controlling glycemic levels and improving diabetes self‐management outcomes.

          • The level of glycemic control and self‐management skills were improved better through individual and telephone‐based intervention, respectively, in comparing group intervention.

          • Community worker led interventions were effective in improvements in diabetes knowledge and self‐care behaviors; however, nurse‐led interventions were more effective in glycemic control.

          • Better glycemic control was achieved in hospital settings compared with outpatient settings.

          • HL interventions yielded better improvement in self‐management among people with a longer diabetes duration (more than 7 years) than those with short duration of diabetes.

          • It was possible to achieve a significant reduction in HbA1c level after a 3‐month intervention in hospital settings.

          摘要

          糖尿病给世界范围内的患者和社会带来了日益严重的健康和经济负担。控制血糖是降低2型糖尿病(T2DM)发病率和死亡率的必要条件。自我管理是糖尿病管理的主要手段。健康知识(HL)是自我管理活动的主要动力。本综述旨在评估HL干预对2型糖尿病患者血糖控制和自我管理结果的影响。通过检索MEDLINE、CINAHL、PubMed、Cochrane、Scopus和Web of Science,本综述共纳入1997—2021年发表的15篇英文形式发表的采用HL驱动干预,并监测2型糖尿病患者糖化血红蛋白(HbA 1c)和自我管理水平的随机对照试验。研究结果表明,健康素养干预对血糖控制和改善自我管理行为产生积极的影响。通过个人干预和电话干预能够提高患者血糖控制水平和自我管理能力。社区工作者主导的干预措施在改善糖尿病知识和自我护理行为方面是有效的;护士主导的干预措施对血糖控制有效。与门诊患者相比,住院患者的血糖控制效果更好。在糖尿病病程较长(超过7年)的人群中,HL干预能更好地改善自我管理。在医院环境中,经过3个月的干预,HbA 1c水平有可能大幅降低。HL驱动的干预措施对血糖和糖尿病自我管理结果有效。

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          Most cited references55

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          IDF Diabetes Atlas: Global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045

          To provide global, regional, and country-level estimates of diabetes prevalence and health expenditures for 2021 and projections for 2045.
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            Economic Costs of Diabetes in the U.S. in 2017

            (2018)
            OBJECTIVE This study updates previous estimates of the economic burden of diagnosed diabetes and quantifies the increased health resource use and lost productivity associated with diabetes in 2017. RESEARCH DESIGN AND METHODS We use a prevalence-based approach that combines the demographics of the U.S. population in 2017 with diabetes prevalence, epidemiological data, health care cost, and economic data into a Cost of Diabetes Model. Health resource use and associated medical costs are analyzed by age, sex, race/ethnicity, insurance coverage, medical condition, and health service category. Data sources include national surveys, Medicare standard analytical files, and one of the largest claims databases for the commercially insured population in the U.S. RESULTS The total estimated cost of diagnosed diabetes in 2017 is $327 billion, including $237 billion in direct medical costs and $90 billion in reduced productivity. For the cost categories analyzed, care for people with diagnosed diabetes accounts for 1 in 4 health care dollars in the U.S., and more than half of that expenditure is directly attributable to diabetes. People with diagnosed diabetes incur average medical expenditures of ∼$16,750 per year, of which ∼$9,600 is attributed to diabetes. People with diagnosed diabetes, on average, have medical expenditures ∼2.3 times higher than what expenditures would be in the absence of diabetes. Indirect costs include increased absenteeism ($3.3 billion) and reduced productivity while at work ($26.9 billion) for the employed population, reduced productivity for those not in the labor force ($2.3 billion), inability to work because of disease-related disability ($37.5 billion), and lost productivity due to 277,000 premature deaths attributed to diabetes ($19.9 billion). CONCLUSIONS After adjusting for inflation, economic costs of diabetes increased by 26% from 2012 to 2017 due to the increased prevalence of diabetes and the increased cost per person with diabetes. The growth in diabetes prevalence and medical costs is primarily among the population aged 65 years and older, contributing to a growing economic cost to the Medicare program. The estimates in this article highlight the substantial financial burden that diabetes imposes on society, in addition to intangible costs from pain and suffering, resources from care provided by nonpaid caregivers, and costs associated with undiagnosed diabetes.
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              Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study.

              To determine the relation between exposure to glycaemia over time and the risk of macrovascular or microvascular complications in patients with type 2 diabetes. Prospective observational study. 23 hospital based clinics in England, Scotland, and Northern Ireland. 4585 white, Asian Indian, and Afro-Caribbean UKPDS patients, whether randomised or not to treatment, were included in analyses of incidence; of these, 3642 were included in analyses of relative risk. Primary predefined aggregate clinical outcomes: any end point or deaths related to diabetes and all cause mortality. Secondary aggregate outcomes: myocardial infarction, stroke, amputation (including death from peripheral vascular disease), and microvascular disease (predominantly retinal photo-coagulation). Single end points: non-fatal heart failure and cataract extraction. Risk reduction associated with a 1% reduction in updated mean HbA(1c) adjusted for possible confounders at diagnosis of diabetes. The incidence of clinical complications was significantly associated with glycaemia. Each 1% reduction in updated mean HbA(1c) was associated with reductions in risk of 21% for any end point related to diabetes (95% confidence interval 17% to 24%, P<0.0001), 21% for deaths related to diabetes (15% to 27%, P<0.0001), 14% for myocardial infarction (8% to 21%, P<0.0001), and 37% for microvascular complications (33% to 41%, P<0.0001). No threshold of risk was observed for any end point. In patients with type 2 diabetes the risk of diabetic complications was strongly associated with previous hyperglycaemia. Any reduction in HbA(1c) is likely to reduce the risk of complications, with the lowest risk being in those with HbA(1c) values in the normal range (<6.0%).
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                Author and article information

                Contributors
                hassanh@uow.edu.au
                Journal
                J Diabetes
                J Diabetes
                10.1111/(ISSN)1753-0407
                JDB
                Journal of Diabetes
                Wiley Publishing Asia Pty Ltd (Melbourne )
                1753-0393
                1753-0407
                05 July 2023
                September 2023
                : 15
                : 9 ( doiID: 10.1111/jdb.v15.9 )
                : 724-735
                Affiliations
                [ 1 ] School of Health & Society, Faculty of the Arts, Social Sciences and Humanities University of Wollongong Wollongong New South Wales Australia
                [ 2 ] Discipline of Medical and Exercise Science, Faculty of Science, Medicine and Health, School of Medicine University of Wollongong Wollongong New South Wales Australia
                Author notes
                [*] [* ] Correspondence

                Hassan Hosseinzadeh, 1 Northfield AVE, Gwynneville New South Wales 2500, Wollongong, Australia.

                Email: hassanh@ 123456uow.edu.au

                Author information
                https://orcid.org/0000-0001-7309-9599
                https://orcid.org/0000-0002-8638-5372
                Article
                JDB13436
                10.1111/1753-0407.13436
                10509520
                37407516
                c7784ba7-3941-4160-bdb5-ac6f164b9efc
                © 2023 The Authors. Journal of Diabetes published by Ruijin Hospital, Shanghai Jiaotong University School of Medicine and John Wiley & Sons Australia, Ltd.

                This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

                History
                : 02 May 2023
                : 03 June 2023
                Page count
                Figures: 4, Tables: 2, Pages: 12, Words: 6593
                Categories
                Review Article
                Review Articles
                Custom metadata
                2.0
                September 2023
                Converter:WILEY_ML3GV2_TO_JATSPMC version:6.3.4 mode:remove_FC converted:20.09.2023

                Endocrinology & Diabetes
                diabetes mellitus type 2,glucose control and clinical trials,health literacy,self‐management,2型糖尿病,血糖控制和临床试验,健康素养,自我管理

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