Roux-en-Y Gastric Bypass Vs Sleeve Gastrectomy in Super Obesity: a Systematic Review and Meta-Analysis.

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Abstract

Laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG) are safe procedures that may present sub-optimal results in superobesity (SO). A meta-analysis was performed aiming to summarize the available evidence on weight loss (primary outcome) and comorbidities resolution of LRYGB and LSG in patients with SO (BMI ≥ 50 kg/m2). From the 16 included studies, 7 integrated the meta-analysis. LRYGB showed a significantly higher weight loss at 6 to 12-months, but not after 24 months and a higher dyslipidemia resolution at 12 months. When compared with LSG, LRYGB achieved better weight loss after 6 and 12 months and higher dyslipidemia resolution after 1 year. There were no significant differences for resolution of the other co-morbidities studied.

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Author and article information

Journal

Journal ID (iso-abbrev): Obes Surg

Title: Obesity surgery

Publisher: Springer Science and Business Media LLC

ISSN (Electronic): 1708-0428

ISSN (Print): 0960-8923

Publication date (Electronic): Jan 2022

Volume: 32

Issue: 1

Affiliations

[1 ] Faculty of Medicine, University of Porto, Alameda Prof. Hernâni Monteiro, 4200-319, Porto, Portugal.

[2 ] Faculty of Medicine, University of Porto, Alameda Prof. Hernâni Monteiro, 4200-319, Porto, Portugal. andrecostapinho@gmail.com.

[3 ] Obesity Integrated Responsibility Unit (CRI-O), São João University Medical Center, 4099-001, Porto, Portugal. andrecostapinho@gmail.com.

[4 ] Surgery Department, São João University Medical Center, 4099-001, Porto, Portugal.

[5 ] Obesity Integrated Responsibility Unit (CRI-O), São João University Medical Center, 4099-001, Porto, Portugal.

[6 ] Instituto de Medicina Molecular João Lobo Antunes, 1649-028, Lisbon, Portugal.

Article

Publisher Item ID: 10.1007/s11695-021-05745-8

DOI: 10.1007/s11695-021-05745-8

PubMed ID: 34642872

SO-VID: d53b079e-91b2-458f-be5c-8b3b575dea49

History

Keywords: Super obesity,Weight loss,Meta-analysis,Laparoscopic sleeve gastrectomy,Comorbidity resolution,Bariatric surgery,LSG,Laparoscopic Roux-en-Y gastric bypass,LRYGB

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Keywords: Super obesity, Weight loss, Meta-analysis, Laparoscopic sleeve gastrectomy, Comorbidity resolution, Bariatric surgery, LSG, Laparoscopic Roux-en-Y gastric bypass, LRYGB

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