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      What we have changed our minds about: Part 2. Borderline personality disorder, epistemic trust and the developmental significance of social communication

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          Abstract

          In Part 1 of this paper, we discussed emerging evidence suggesting that a general psychopathology or ‘p’ factor underlying the various forms of psychopathology should be conceptualized in terms of the absence of resilience, that is, the absence of positive reappraisal mechanisms when faced with adversity. These impairments in the capacity for positive reappraisal seem to provide a comprehensive explanation for the association between the p factor and comorbidity, future caseness, and the ‘hard-to-reach’ character of many patients with severe personality pathology, most notably borderline personality disorder (BPD). In this, the second part of the paper, we trace the development of the absence of resilience to disruptions in the emergence of human social communication, based on recent evolutionary and developmental psychopathology accounts. We argue that BPD and related disorders may be reconceptualized as a form of social understanding in which epistemic hypervigilance, distrust or outright epistemic freezing is an adaptive consequence of the social learning environment. Negative appraisal mechanisms become overriding, particularly in situations of attachment stress. This constitutes a shift towards a more socially oriented perspective on personality psychopathology in which the absence of psychological resilience is seen as a learned response to the transmission of social knowledge. This shift in our views has also forced us to reconsider the role of attachment in BPD. The implications for prevention and intervention of this novel approach are discussed.

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          Animal behaviour: cognitive bias and affective state.

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            Rethinking the theoretical foundation of sociobiology.

            Current sociobiology is in theoretical disarray, with a diversity of frameworks that are poorly related to each other Part of the problem is a reluctance to revisit the pivotal events that took place during the 1960s, including the rejection of group selection and the development of alternative theoretical frameworks to explain the evolution of cooperative and altruistic behaviors. In this article, we take a "back to basics" approach, explaining what group selection is, why its rejection was regarded as so important, and how it has been revived based on a more careful formulation and subsequent research. Multilevel selection theory (including group selection) provides an elegant theoretical foundation for sociobiology in the future, once its turbulent past is appropriately understood.
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              A conceptual framework for the neurobiological study of resilience.

              The well-replicated observation that many people maintain mental health despite exposure to severe psychological or physical adversity has ignited interest in the mechanisms that protect against stress-related mental illness. Focusing on resilience rather than pathophysiology in many ways represents a paradigm shift in clinical-psychological and psychiatric research that has great potential for the development of new prevention and treatment strategies. More recently, research into resilience also arrived in the neurobiological community, posing nontrivial questions about ecological validity and translatability. Drawing on concepts and findings from transdiagnostic psychiatry, emotion research, and behavioral and cognitive neuroscience, we propose a unified theoretical framework for the neuroscientific study of general resilience mechanisms. The framework is applicable to both animal and human research and supports the design and interpretation of translational studies. The theory emphasizes the causal role of stimulus appraisal (evaluation) processes in the generation of emotional responses, including responses to potential stressors. On this basis, it posits that a positive (non-negative) appraisal style is the key mechanism that protects against the detrimental effects of stress and mediates the effects of other known resilience factors. Appraisal style is shaped by three classes of cognitive processes--positive situation classification, reappraisal, and interference inhibition--that can be investigated at the neural level. Prospects for the future development of resilience research are discussed.
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                Author and article information

                Contributors
                p.fonagy@ucl.ac.uk
                Journal
                Borderline Personal Disord Emot Dysregul
                Borderline Personal Disord Emot Dysregul
                Borderline Personality Disorder and Emotion Dysregulation
                BioMed Central (London )
                2051-6673
                11 April 2017
                11 April 2017
                2017
                : 4
                : 9
                Affiliations
                [1 ]GRID grid.83440.3b, Research Department of Clinical, Educational and Health Psychology, , University College London, ; London, UK
                [2 ]GRID grid.5596.f, Faculty of Psychology and Educational Sciences, , KU Leuven, ; Leuven, Belgium
                Author information
                http://orcid.org/0000-0003-0229-0091
                Article
                62
                10.1186/s40479-017-0062-8
                5387344
                28405338
                d793295f-3d08-436a-97f1-ca4a1729157e
                © The Author(s). 2017

                Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

                History
                : 7 March 2017
                : 21 March 2017
                Funding
                Funded by: FundRef http://dx.doi.org/10.13039/501100000272, National Institute for Health Research;
                Award ID: NF-SI-0514-10157
                Award Recipient :
                Categories
                Review
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                © The Author(s) 2017

                borderline personality disorder,resilience,epistemic trust,mentalizing,attachment,psychopathology

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