It is feasible to predict delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (aSAH) using Artificial intelligence (AI) algorithms, which may offer significant improvements in early diagnosis and patient management. This systematic review and meta-analysis evaluate the efficacy of machine learning (ML) in predicting DCI, aiming to integrate complex clinical data to enhance diagnostic accuracy. We searched PubMed, Scopus, Web of science, and Embase databases without restrictions until June 2024, applying PRISMA guidelines. Out of 1498 studies screened, 10 met our eligibility criteria involving ML approaches in patients with confirmed aSAH. The studies employed various ML algorithms and reported differential ML metrics outcomes. Meta-analysis was performed on eight studies, which resulted in a pooled sensitivity of 0.79 [95% CI: 0.63-0.89], specificity of 0.78[95% CI: 0.68-0.85], positive DLR of 3.54 [95% CI: 2.22-5.64] and the negative DLR of 0.28 [95% CI: 0.15-0.52], diagnostic odds ratio of 12.82 [95% CI: 4.66-35.28], the diagnostic score of 2.55 [95% CI: 1.54-3.56], and the area under the curve (AUC) of 0.85. These findings show significant diagnostic accuracy and demonstrate the potential of ML algorithms to significantly improve the predictability of DCI, implying that ML could impart a significant role on improving clinical decision making. However, variability in methodological approaches across studies shows a need for standardization to realize the full benefits of ML in clinical settings.

High-grade glioma (HGG) is an aggressive brain tumor with poor survival rates. Predicting survival outcomes is critical for personalized treatment planning. In recent years, artificial intelligence (AI), particularly machine learning (ML) and deep learning (DL) models, has emerged as a promising approach for enhancing prognostic accuracy in HGG but this study especially focused on the potential of AI in the recurrence of HGG. A systematic review and meta-analysis were conducted to assess the performance of AI-based models in predicting survival outcomes for HGG patients. Relevant studies were retrieved from PubMed, Embase, Scopus, and Web of Science until 2 Dec 2024, using predefined keywords ("High-Grade Glioma", "Survival" and "Machine Learning") without date or language restrictions. Data extraction and quality assessment were performed in accordance with PRISMA and PROBAST guidelines. In this study were included. The pooled diagnostic metric, the area under the curve (AUC), was analyzed using random-effects models. A total of 39 studies with 29 various algorithms and 79,638 patients were included, with 15 studies contributing to the meta-analysis. The most commonly used algorithms were random forest (RF) and logistic regression (LR), which demonstrated robust predictive accuracy. The pooled AUCs for one-year, two-year, three-year and overall survival predictions were 0.816, 0.854, 0.871 and 0.789 respectively. Subgroup analysis revealed that RSF achieved the highest predictive accuracy with an AUC of 0.91 (95% CI: 0.84-0.98), while LR followed with an AUC of 0.89 (95% CI: 0.82-0.96). Models integrating clinical, radiomics, and genetic features consistently outperformed single-data-type models. MRI was the most frequently utilized imaging modality. AI-based models, particularly ML and DL algorithms, show significant potential for improving survival prediction in HGG patients. By integrating multimodal data, these models offer valuable tools for personalized treatment planning, although further validation in prospective, multicenter studies is needed to ensure clinical applicability.

An important source of long range forecast skill for the North Atlantic Oscillation (NAO) comes from predictability of tropical rainfall. While the El Niño Southern Oscillation (ENSO) is a better-known driver of the NAO, the Indian Ocean Dipole (IOD) also has an influence, particularly when ENSO is inactive. Given future projected changes to ENSO and the IOD, it is important to understand how the IOD–NAO teleconnection may evolve. Here we use climate model simulations to investigate the IOD and its NAO teleconnection. We find that the IOD itself changes considerably under climate change, with a weakening of the present-day anticorrelation between the dipole nodes and a westward shift in the IOD pattern. While historical model simulations reproduce the IOD–NAO teleconnection pathway seen in observational analyses, the teleconnection is projected to weaken in future, with the weakening linked to the westward IOD shift.

Autism spectrum disorder (ASD) is one of the complicated neurodevelopmental disorders that impacts the daily functioning and social interactions of individuals. It includes diverse symptoms and severity levels, making it challenging to diagnose and treat efficiently. Various deep learning (DL) based methods have been developed for diagnosing ASD, which rely heavily on behavioral assessment. However, existing techniques have suffered from poor diagnostic outcomes, higher computational complexity, and overfitting issues. To address these challenges, this research work introduces an innovative framework called 3T Dilated Inception Network (3T-DINet) for effective ASD diagnosis using resting-state functional Magnetic Resonance Imaging (rs-fMRI) images. The proposed 3T-DINet technique designs a 3T dilated inception module that incorporates dilated convolutions along with the inception module, allowing it to extract multi-scale features from brain connectivity patterns. The 3T dilated inception module uses three distinct dilation rates (low, medium, and high) in parallel to determine local, mid-level, and global features from the brain. In addition, the proposed approach implements Residual networks (ResNet) to avoid the vanishing gradient problem and enhance the feature extraction ability. The model is further optimized using a Crossover-based Black Widow Optimization (CBWO) algorithm that fine-tunes the hyperparameters thereby enhancing the overall performance of the model. Further, the performance of the 3T-DINet model is evaluated using the five ASD datasets with distinct evaluation parameters. The proposed 3T-DINet technique achieved superior diagnosis results compared to recent previous works. From this simulation validation, it's clear that the 3T-DINet provides an excellent contribution to early ASD diagnosis and enhances patient treatment outcomes.